Description
Mood imbalance is one of the most prevalent concerns affecting an individual’s quality of life. Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter involved in several crucial physiological processes, especially in modulating mood, cognition, sleep, appetite, learning, memory, and vasoconstriction.[1] Serotonin is synthesized in the intestinal tract as well as in the central nervous system.
Inadequate levels of serotonin in the brain have been associated with several disorders.[1]
5‑Hydroxytryptophan (5‑HTP) derived from the seed of Griffonia simplicifolia is a natural precursor needed for the synthesis of serotonin as well as for the neurohormone melatonin.[2] Orally administered serotonin is not able to cross the blood-brain barrier and therefore cannot enter the CNS.[1, 2] 5‑HTP, however, is able to cross the blood-brain barrier, where it can then be utilized as a precursor to raise serotonin levels safely and effectively.[2, 3]
NFH 5-HTP SAP can